Dear Editor-in-Chief,
       Non-communicable diseases (NCDs)—including cardiovascular diseases, diabetes, cancers, and chronic respiratory diseases—are the leading cause of premature mortality in Iran, accounting for 81% of such deaths, which exceeds the global average of approximately 71%. This increasing burden reflects a broader global trend; worldwide, NCDs are responsible for the majority of deaths, with their prevalence rising steadily, particularly in low- and middle-income countries. In Iran, factors such as lifestyle changes, urbanization, and demographic shifts have significantly contributed to escalating rates of obesity, hypertension, and diabetes. Urgent action is required through effective preventive interventions, promotion of healthy lifestyle habits, and comprehensive public health strategies aligned with successful international examples to address this critical public health challenge.