Masumeh Saeidi Health Providers 2820-9192 5 1 2025 06 01 Effect of Auriculotherapy and Vitamins on the Outcomes of Assisted Reproductive Technologies and Mental Health in Infertile Women 97 108 221583 10.22034/hp.2025.525916.1066 EN Maryam Mirzaei Department of Obstetrics and Gynecology, Faculty of Medicine, Jiroft University of Medical Sciences, Jiroft, Iran. 0000-0003-2758-853X Journal Article 2025 05 24 Background: Infertility adversely affects women’s physical and mental health. Although assisted reproductive technologies (ART) like IVF provide hope, outcomes are uncertain and the process is stressful. Recently, auriculotherapy (ear acupuncture) and vitamin supplementation have gained attention for their potential to enhance ART success and psychological well-being. This review summarizes current evidence on these interventions in infertile women. Materials and Methods: In this review, two independent reviewers systematically searched Scopus, EMBASE, PubMed, the Cochrane Library, Web of Science, and the Google Scholar search engine for studies published up to March 2025. The search included randomized controlled trials and observational studies examining auriculotherapy and vitamin supplementation in relation to ART outcomes and mental health in infertile women. Keywords used included "auriculotherapy," "vitamins," "ART," "infertility," and "mental health". Results: Auriculotherapy and vitamin supplementation have shown benefits for infertile women undergoing ART. Studies indicate auriculotherapy can reduce stress and anxiety, which are linked to improved clinical pregnancy and implantation rates, and sometimes higher live birth rates. It may also help regulate reproductive hormones (FSH, LH, and estradiol), and immune cytokines, supporting embryo implantation. Vitamin supplementation, especially with B vitamins, vitamin D, and antioxidants (such as vitamins C and E), supports ovarian function, hormonal balance, and mental health. Combining these interventions with standard ART protocols may have synergistic effects, potentially improving pregnancy rates and psychological well-being. Both approaches are generally safe, though individual responses vary, highlighting the need for further research. Conclusion: Auriculotherapy and vitamin supplementation appear to be effective supportive therapies for infertile women undergoing ART. While current evidence is promising, more rigorous research is needed to confirm their benefits and to develop standardized, individualized treatment protocols.

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